Sunday, September 28, 2008

Death Rates From Prescription Drugs Explode at the Beginning of Each Month


According to research, deaths attributed to medication errors rise by as much as 25 percent above normal in the first few days of every month. This study is the first to document a beginning-of-the-month boost in deaths associated with mistakes in prescription drugs.

The Problem

The primary culprit behind these death rates: A beginning-of-the-month increase in pharmacy workloads and a consequential increase in their error rates. To offer a further explanation of this occurrence, one sociologist stated, "Government assistance payments to the old, sick and the poor are typically received at the beginning of each month. Because of this, there is a beginning-of-the-month spike in purchases of prescription medications."

However, further findings suggest otherwise.

Researchers examined all United States death certificates from 1970 to 2000 to analyze some 131,000 deaths caused by fatal poisoning accidents from drugs. They found that a small number (3 percent) of the deaths were from adverse effects of the right drug taken at the right dose, while the majority of deaths (97 percent) resulted from medication errors:

  • Wrong dose given or taken
  • Accidental overdose of a drug
  • A drug taken inadvertently

It was also discovered that the beginning-of-the-month spike in deaths was apparent in the young and well as in the elderly and poor, indicating the problem is partially due to pharmacy error.

(The study did not include specific clinical information regarding prescription type, dosage or days supply, nor did it include deaths associated with overdose of street drugs or from intentional poisoning.)

The Solution

In order to reduce the medication-error death rate researchers recommended:

  • Pharmacies to consider increasing staffing levels at the beginning of each month
  • Government officials to consider spreading assistance payments out over the entire month, rather than the beginning
  • Both patients and clinical staff to make a special effort to check the accuracy of their prescriptions at the beginning of each month

Science Daily January 6, 2005

8 Drugs that Doctors would never use

Doctors know which prescription and over-the-counter drugs are the most dangerous. The writers of this article asked them the question, "Which medications would you skip?" Here were their answers:

Advair

It‘s asthma medicine that can make your asthma deadly. Advair contains the long-acting beta-agonist (LABA) salmeterol. A 2006 analysis found that regular use of LABAs can increase the severity of an asthma attack. Researchers estimate that salmeterol may contribute to as many as 5,000 asthma-related deaths in the United States each year.

Avandia

Diabetes is destructive enough on its own, but if you try to control it with rosiglitazone, better known as Avandia, it could cause a heart attack. A study found that people who took rosiglitazone for at least a year increased their risk of heart failure or a heart attack by 109 percent and 42 percent, respectively.

Celebrex

This painkiller has been linked to increased risks of stomach bleeding, kidney trouble, and liver damage. And according to a 2005 study, people taking 200 mg of Celebrex twice a day more than doubled their risk of dying of cardiovascular disease. Those on 400 mg twice a day more than tripled their risk.

Ketek

This antibiotic, which has traditionally been prescribed for respiratory-tract infections, carries a high risk of severe liver side effects. In February 2007, the FDA limited the usage of Ketek to the treatment of pneumonia.

Prilosec and Nexium

The FDA has investigated a suspected link between cardiac trouble and these acid-reflux remedies, although they did not find a "likely" connection. But whether this is true or not, they can raise your risk of pneumonia, and result in an elevated risk of bone loss. The risk of a bone fracture has been estimated to be over 40 percent higher in patients who use these drugs long-term.

Visine Original

These eye drops “get the red out” by shrinking blood vessels. Overuse of the active ingredient tetrahydrozoline can perpetuate the vessel dilating-and-constricting cycle and may cause even more redness.

Pseudoephedrine

This decongestant, found in many drugs, can raise blood pressure and heart rate, setting the stage for vascular catastrophe. Over the years, pseudoephedrine has been linked to heart attacks and strokes, as well as worsening the symptoms of prostate disease and glaucoma.

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